LEUKEMIA

  • Leukemia is cancer of the body’s blood-forming tissues, including the bone marrow and the lymphatic system.
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  • Many types of leukemia exist. Some forms of leukemia are more common in children. Other forms of leukemia occur mostly in adults.
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  • Leukemia usually involves the white blood cells, potent infection fighters — they normally grow and divide in an orderly way, as your body needs them. But in people with leukemia, the bone marrow produces an excessive amount of abnormal white blood cells, which don’t function properly.
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  • Treatment for leukemia can be complex — depending on the type of leukemia and other factors.
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Rate of New Cancers in the United States, 2019 Leukemias, All Ages, All Races and
Ethnicities, Male and Female

Source – U.S. Cancer Statistics Working Group. U.S. Cancer Statistics Data Visualizations Tool, based on 2021 submission data (1999-2019): U.S. Department of Health and Human Services, Centers for Disease Control and Prevention and National Cancer Institute; https://www.cdc.gov/cancer/dataviz, released in June 2022.

Top 10 Cancers by Rates of Cancer Deaths
United States, 2019

Rate per 100,000 people

Source – U.S. Cancer Statistics Working Group. U.S. Cancer Statistics Data Visualizations Tool, based on 2021 submission data (1999-2019): U.S. Department of Health and Human Services, Centers for Disease Control and Prevention and National Cancer Institute; https://www.cdc.gov/cancer/dataviz, released in June 2022.

Top 10 Cancers by Rates of New Cancer Cases
United States, 2019

Rate per 100,000 people

Source – U.S. Cancer Statistics Working Group. U.S. Cancer Statistics Data Visualizations Tool, based on 2021 submission data (1999-2019): U.S. Department of Health and Human Services, Centers for Disease Control and Prevention and National Cancer Institute; https://www.cdc.gov/cancer/dataviz, released in June 2022.

TRADITIONAL DIAGNOSTIC TOOLS OF LEUKEMIA

  • Leukemia is typically diagnosed via abnormal results on a full blood count followed by an examination of a blood film.
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  • The diagnosis is usually confirmed on a bone marrow aspirate and/or trephine biopsy looking at cell morphology and bone marrow architecture.
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  • Additional techniques that may be used to further classify the type of leukemia include flow cytometric immunophenotyping and genetic studies.
NEW TREND

DIAGNOSTIC TOOLS OF LEUKEMIA

  • Genetic studies are crucially important for the diagnosis of leukemia, especially with regards to prognosis and therapeutic choice.
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  • 1. Commonly used genetic techniques at diagnosis of leukemia include:
  •   – G-ban metaphase cytogenetics.
  •   – fluorescence in situ hybridization (FISH), and in vitro molecular techniques           (e.g. comparative genomic hybridization,SNP arrays, and PCR-based              
            techniques).
  • 2. “LENA Q51®” Screening Kit is a qualitative in vitro diagnostic test for screening 52 fusion genes.